Interleukin
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- proteins for communication by and for leukocytes
- control production and activation
IL-1
Stem cell to Myeloid line
Lymphocyte to T Lymphocyte
IL-2
Stem cell to Lymphoid line
Lymph to T Lymph
IL-3
Stem cell to Myeloid line
Common myeloid progenitor to Megakaryocyte and RBC
Meyloid blast to all granulocytes and monocytes
IL-4
Lymph to T lymph
IL-5
Myeloid blast to eosinophils
also used by T lymphs ?
IL-6
Stem cell to myeloid line
basophil, neutrophil and monocytes but not eosinophil (so unregulated in bacterial infections?)
GM-CSF
Ganulocyte-Macrophage Colony Stimulating Factor
All granulocytes and monocytes
Includes megakaryocytes, RBCs and basically all earlier cells (all except lymphoid lineage)