Interleukin

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- proteins for communication by and for leukocytes

- control production and activation


IL-1

Stem cell to Myeloid line

Lymphocyte to T Lymphocyte


IL-2

Stem cell to Lymphoid line

Lymph to T Lymph


IL-3

Stem cell to Myeloid line

Common myeloid progenitor to Megakaryocyte and RBC

Meyloid blast to all granulocytes and monocytes


IL-4

Lymph to T lymph


IL-5

Myeloid blast to eosinophils

also used by T lymphs ?


IL-6

Stem cell to myeloid line

basophil, neutrophil and monocytes but not eosinophil (so unregulated in bacterial infections?)


GM-CSF

Ganulocyte-Macrophage Colony Stimulating Factor

All granulocytes and monocytes

Includes megakaryocytes, RBCs and basically all earlier cells (all except lymphoid lineage)